Previous edition: 2019.

First puhblished in 1999.

Includes index.

Section 1: Introduction. Biochemistry and clinical medicine: Introduction and overview - Section 2: Molecules and cells. Amino acids and proteins -- Carbohydrates and lipids -- Membranes and transport - Section 3: Metabolism. oxygen transport -- Catalytic proteins: enzymes -- Vitamins and minerals -- Bioenergetics and oxidative metabolism -- Glycolysis and the pentose phosphate pathway -- The tricarboxylic acid cycle -- Fatty acid and triglyceride catabolism -- Biosynthesis and storage of carbohydrate -- Biosynthesis and storage of fatty acids -- Biosynthesis of cholesterol and steroids -- Biosynthesis and degradation of amino acids -- Biosynthesis and degradation of nucleotides -- Complex carbohydrates: glycoproteins -- Complex lipids -- The extracellular matrix - Section 4: Molecular basis of inheritance. Deoxyribonucleic acid -- Ribonucleic acid -- Protein synthesis and turnover -- Regulation of gene expression: basic mechanisms -- Genomics, proteomics, and metabolomics - Section 5: Signalling and growth. Membrane receptors and signal transduction - Neurotransmitters -- Biochemical endocrinology -- Cellular homeostasis: cell growth and cancer - Aging - Section 6: Fuels, nutrients and minerals. Digestion and absorption of nutrients: the gastrointestinal -- Glucose homeostasis and fuel metabolism: diabetes mellitus -- Nutrients and diets -- Lipoprotein metabolism and atherogenesis -- Section 7: Specialized tissues and their function. Role of the liver in metabolism -- Water and electrolytes homeostasis -- The lung and the regulation of hydrogen ion concentration (Acid-base balance) -- Muscle: energy metabolism, contraction, and exercise -- Bone metabolism and calcium homeostasis - Neurochemistry -- Section 8: Blood and immunity. Clinical biochemistry. Blood and plasma proteins -- Hemostasis and thrombosis -- Oxidative stress and inflammation -- The immune response: innate and adaptive immunity

"Written by carefully selected global experts, practicing physicians, and educators in the various sub-disciplines of biochemistry, Medical Biochemistry, 6th Edition, offers a unique combination of research and clinical practice tailored to today's integrated courses. Covering clinically relevant topics in greater detail than other texts, this outstanding resource provides a strong overview of traditional areas in medical biochemistry along with state-of-the-art coverage of today's latest developments. You'll learn basic science concepts alongside clinical cases that describe patients likely to be encountered in clinical training, as well as how to use laboratory tests to diagnose and monitor the most important conditions. Thorough yet accessible, this clinically focused text is useful from medical school to clinical practice."-- Publisher's description